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Nervous System Regulation: A Clinical Overview for Practitioners and Informed Clients

Polyvagal-informed overview of nervous system dysregulation in adults. Covers the three-state ANS model, individual dysregulation thresholds, and evidence-based regulation tools including breathing, vagal stimulation, movement, co-regulation, and somatic therapies. Addresses what is less effective than commonly presented. Neurodivergent nervous systems covered separately. Free toolkit and full article available at Mindpath Academy.

Melanie Du Preez
MelanieClinical Psychologist
2 min read
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Nervous System Regulation: A Clinical Overview for Practitioners and Informed Clients

Polyvagal Theory (Porges, 2011) has moved from specialist clinical literature into mainstream mental health discourse with both useful and distorting consequences. This article offers a clinically grounded overview of what nervous system regulation means, what dysregulates it, and what the evidence supports — written for an informed adult audience rather than a clinical training context.

The piece covers the three-state ANS model (ventral vagal, sympathetic, dorsal vagal), the factors that influence individual dysregulation thresholds (early experience, chronic stress load, trauma history, neurobiology), and the symptom profiles associated with chronic sympathetic activation versus dorsal vagal collapse. It addresses the evidence base for self-directed regulation tools — extended exhale breathing, non-invasive vagal stimulation, slow rhythmic movement, co-regulation, somatic therapies, and MBSR/MBCT — and explicitly addresses what is less effective than commonly presented, including cold exposure, alcohol, and cognitive reframing in the absence of physiological downregulation.

A section on neurodivergent nervous systems notes that sensory processing differences and the chronic load of masking produce a distinct dysregulation profile requiring calibrated intervention.

A free five-page clinical toolkit and the full psychoeducational article are available at Mindpath Academy for clients and referring practitioners.


Dr Melanie du Preez | HPCSA-registered Clinical Psychologist | 26 years clinical experience | Founder, Mindpath Academy | Maudsley/FBT-certified | Specialisations: neurodivergence, trauma, burnout, LGBTQ+ mental health

Tags

nervous system regulation, polyvagal theory, vagus nerve, somatic therapy, trauma, anxiety, burnout, EMDR, mindfulness, neurodivergence, clinical psychology

About the Author

Melanie Du Preez

Melanie Du Preez

Clinical Psychologist

Specializations
Stress or AnxietyTrauma or PTSDGrief or Loss
About

I'm a practitioner with a PhD and 26 years of experience — which sounds very official until you factor in that I'm also a late-diagnosed AuDHD adult who spent most of those years wondering why everything felt slightly harder than it seemed to for everyone else. That context matters. It shapes how I work, how I listen, and how I explain things. I'm based in South Africa and work online with clients internationally. I specialise in neurodivergence, eating disorders, trauma, anxiety, and the kind of chronic low-grade overwhelm that doesn't always have a clean diagnostic label. I use evidence-based approaches — primarily BWRT, ACT, DBT, and CBT — but I adapt them to the person in front of me, not the other way around. I'm also a published author and Udemy course creator, because I believe good psychoeducation shouldn't be locked behind a therapy door. Here's the thing: I'm not the practitioner who'll nod politely and hand you a worksheet. I'm the one who'll actually explain what's happening in your brain and help you figure out what to do about it.

Nervous System Regulation: A Clinical Overview for Practitioners and Informed Clients | Shemesh Health Blog | Shemesh Health